|
The milling action of the particle is because of the high velocity of air/gases instead of pins, jaws or hammers and because of this heat does not get generated during milling. The adiabatic expansion of compressed air takes place with the resultant cooling effect. The heat sensitive and low melting point materials are micronized without use of freeze
The micronization takes place due to the collision between the incoming particles and the particles, which are accelerated into the spiral path. The larger particles of the product get retained at the periphery of the chamber by centrifugal force and the smaller particles exit with the exhaust air from the central port of the chamber.
The material can be milled to an average particle size 0.2 to 5 micron or coarse ground to 400 mesh depending upon Characteristics of the product.
The micronizing of the powder improves better absorption of the drugs in the human system. The instantaneous increase of surface area due to micronizing, results in new and unusual chemical and physical properties relating to suspendability, solid-state reaction rate, texture, colour and absorption.
The surface area achieves increase in potency of drugs, which reduces the dosage of the drugs. A 30 mesh product when milled to 5 micron has more than 160,000 particles & surface area more than 115 times. This results into faster reaction time for chemicals, faster ignition time in solid fuels rockets. The Jet Milled pesticides & herbicides cover much more surface area using less of the active ingredient, thus reducing the cost. The polishing powders used for polishing the lenses, computer hard disc or toothpaste are required to be a narrow particle size distribution for maximum productivity. The abrasives used in these polishing are very precisely milled.
The facial cosmetics gives a silky smoothness when in Jet Mill, which is a very important property. The reflectivity of light occurs when the particle size of the pigment approaches a precise relationship to the wavelength of visible light. Therefore controlling the particle size, the product colour & brilliance can be controlled.
PROMASTM Jet mill versions are sanitary, Indian FDA and US-FDA accepted design, in line with GMP practices and in accordance with all pharmaceutical specification worldwide. The jet mills manufactured by us have replaceable internal rings with optimized grinding angles for various products. The design & construction of PromasTM jet mills are the result of many years experience in the engineering industries. They are truly effective jet mills that can be counted on for many years of dependable, uninterrupted service. PromasTM has successfully developed all the models of micronizers and presently supplied are 4', 8', 12' and 16' models. The main milling chamber is mounted on fully stainless steel stand with all the process pressure regulators, gauges, controls valves and magnahelic gauges to monitor pressure across the filters are mounted in the front panel of the chamber so as to have ease of user friendly operations. The jet mill disassembles in more parts without threads for perfect cleaning of components and fast changeover, without risk of cross-contamination.
|